Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent
Figure 3
Combined survival plots of BALB/c mice following passive transfer of human serum from vaccines 35 days after receiving different doses of vaccine. Study (2), per group. Mice were administered 250 μL human serum into the peritoneal cavity, 3 hours before being exposed to more than 10 LD50 aerosolised Y. pestis using a modified contained Henderson apparatus. The median time to death (MTD) was calculated using a Kaplan-Meier survival plot.
