Attenuation and Immunogenicity of a Live High Pathogenic PRRSV Vaccine Candidate with a 32-Amino Acid Deletion in the nsp2 Protein

Table 3

Nine unique amino acids positions that varied in PRRSV attenuation process.

VR-2332/RespPRRSV-MLV	JXA1/JXA1R	HuN4/HuN4-F112	TJ/TJM	QY1/QY100
GP2 (L10/F10)	GP2 (L10/F10)			GP2 (L10/F10)*
	GP2 (Y50/F50)	GP2 (Y50/S50)		GP2 (Y50/F50)
		GP2 (I118/V118)		GP2 (I118/V118)
E (D9/Y9)	E (D9/N9)	E (D9/N9)		E (D9/N9)
	E (L48/F48)	E (L48/F48)		E (L48/F48)
	GP3 (H79/N79)		GP3 (F143/L143)	GP3 (H79/N79)
	GP4 (D43/G43)	GP4 (D43/N43)	GP4 (D43/G43)	GP4 (D43/N43)
			GP5 (G80/V80)	GP5 (G80/V80)
		GP5 (Q196/R196)	GP5 (Q196/R196)	GP5 (Q196/R196)

∗Synonymous mutation.