|
| Viruses and vectors | Inserted gene | Host | Neutralizing Ab | | Other responses | Reference |
|
| PRRSV | | | | | | |
| Canine adenovirus type 2 | GP5 and M | Mouse | Appeared at 14 days post immunization (dpi) peaked at 42 dpi maximum titer = 16 | | Anti-PRRSV Ab appeared at 14 dpi; CTL appeared at 28 dpi | [7] |
| Adenovirus | GP5 and M | Mouse | Appeared at 14 dpi peaked at 56 dpi, maximum titer = 102 | | Specific lymphocyte proliferation responses appeared at 28 dpi; CTL appeared at 28 dpi | [69] |
| MVA (Poxvirus) | GP5 and M | Mouse | Appeared at 14 dpi peaked at 70 dpi maximum titer = 8.12 | | High IFN- (72.6 pg/mL) | [60] |
| Baculovirus | GP5 and M | Mouse | Appeared at 21 dpi peaked at 42 dpi maximum titer = 8 | | High IFN-γ (147.84 pg/mL) | [52] |
| PRV | GP5 and M | Mouse | Appeared at 42 dpi peaked at 70 dpi maximum titers = 21.3 | | | [11] |
| | GP5m and M | Piglets | Appeared at 42 dpi peaked at 84 dpi maximum titer = 160 | | Anti-PRRSV Ab appeared at 28 dpi | |
|
| PCV2 | | | | | | |
| Adenovirus | ORF2 | Piglets | Titers = 1 : 36 (27 dpi) and 1 : 48 (37 dpi) | | Specific Ab appeared at 10 dpi; protection = 60% | [55] |
| Baculovirus | ORF2 | Mouse | Appeared at 21 dpi peaked at 42 dpi maximum titer = 16 | | Specific Ab appeared at 21 dpi; high IFN-γ (286 pg/mL) | [70] |
| PRV | ORF2 | Piglets | Appeared at 21 dpi
PCV2 Ab not detected | | Specific Ab appeared at 21 dpi; PCV2-specific lymphocyte proliferation appeared at 49 dpi (low) | [71] |
|
| FMDV | | | | | | |
| Adenovirus | whole capsid and non-structural protein 3C | Piglets | non-detected | | Protection = 75% low FMDV Ab | [72] |
| Fowlpox virus (Poxvirus) | whole capsid and non-structural protein 3C | Mouse | | | Specific Ab appeared at 10 dpi | |
| | | Piglets | Peaked at 30 dpi decreased by 49 dpi | | Specific Ab appeared at 10 dpi; protection = 75% | [21] |
| Pseudotype baculovirus | whole capsid and non-structural protein 3C | Mouse | Titer = 13 (21 dpi)
Titer = 35 (49 dpi) | | High IFN- (1917 pg/mL) | [73] |
| PRV | whole capsid and non-structural protein 3C | Piglets | Appeared at 21 dpi (variable) | | Virus-specific lymphocyte and non-proliferative responses higher than recombinant; protection = 60% | [63] |
|
| CSFV | | | | | | |
| Adenoviruses | E2 glycoprotein | Rabbits | Titer = 13.8 (21 dpi)
Titer = 218.8 (35 dpi) | | | [43] |
| | | Piglets | Antibody level was at 90% inhibition rate | | Protection = 40% | |
| Orf virus (Poxvirus) | E2 glycoprotein | Piglets | Appeared at 21 dpi
Titer = 37 (49 dpi) | | Protection = 100% | [74] |
| PRV | E2 glycoprotein | Piglets | Appeared at 42 dpi
Titer = 37 | | Protection = 100% | [6] |
|
| SIV | | | | | | |
| Adenoviruses | HA gene of type H3N2 | Mouse | Appeared at 14 dpi | | HA inhibiting (HI) Ab appeared at 14 dpi peaked at 35 dpi
Titer = 8;
Maximum titer = 32
Protection = 83.3% | [31] |
| PRV | HA gene of type H3N2 | Mouse | | | HI Ab appeared at 21 dpi Peaked at 42 dpi
Titer = 2
Maximum titer = 4 Protection = 80%. | [9] |
|
