Analysis of a Functional IL-6 Gene Polymorphism in HLAB27 Associated and Intermediate Uveitis Gives New Insight in Disease Pathogenesis and Commonality with Other Autoimmune Diseases
Table 2
Baseline ocular and systemic parameters.
Patient characteristics
HLAB27 AAU
IU
()
()
Mean age of onset ± SD (years)
35.64 ± 14.10
25.91 ± 14.59
Mean number of flares ± SD
6.93 ± 7.80
4.24 ± 7.17
Mean duration of flares ± SD (weeks)
4.00 ± 2.74
6.02 ± 6.39
Mean duration between flares ± SD (months)
21.19 ± 18.38
11.29 ± 12.10
Secondary cataract
21 (15.67)
11 (13.10)
Secondary glaucoma
5 (3.73)
2 (2.40)
Ankylosing spondylitis
57 (42.54)
0 (0.00)
Juvenile idiopathic arthritis
1 (0.75)
0 (0.00)
Undifferentiated spondyloarthritis
18 (13.43)
0 (0.00)
Reactive arthritis
5 (3.73)
0 (0.00)
Crohn’s disease
1 (0.75)
1 (1.20)
Psoriatic arthritis
12 (9.00)
0 (0.00)
Multiple sclerosis
0 (0.00)
2 (2.40)
HLAB27 AAU: HLAB27 associated acute anterior uveitis. IU: intermediate uveitis. SD: standard deviation. Values are (%) unless otherwise indicated.
