Research Article

Coinfection by Hepatitis C Is Strongly Associated with Abnormal CD4/CD8 Ratio in HIV Patients under Stable ART in Salvador, Brazil

Table 3

Mean HIV-1 RNA plasma viral load and and CD4 count of patients at baseline, according to immune restoration pattern.

Pattern of immune restoration
VariablesInadequate PartialAdequate value
Mean (95% CI)Mean (95% CI)Mean (95% CI)

CD4 nadir
 All patients 89164 (119–173)112230 (199–260)92314 (268–360)<0.001
 Males62121.7 (105.6)208.9 (164.4)336.1 (248.5)<0.001
 Females27204.0 (157.0)38270.5 (155.0)48294.3 (196.7)0.1
Pretherapy plasma viral load (log10)775.0 (4.8–5.1)874.6 (4.5–4.8)734.7 (4.5–4.9)0.01
Mean duration (days) of viral suppression7490740.03
Mean elapsed time (days) between HIV diagnosis and ART initiation (95% CI)77383 (229–537)112636 (436–836)92519 (314–725)NS

12 patients started ART before viral load tests were available in C-HUPES (missing values).