Gamma-Irradiated Bacille Calmette-Guérin Vaccination Does Not Modulate the Innate Immune Response during Experimental Human Endotoxemia in Adult Males

Figure 3

Plasma cytokine concentrations in subjects vaccinated with gamma-irradiated BCG or placebo. In the panels (a–d), median values of proinflammatory cytokines TNF-α, IL-6, IL-8, and MCP-1 are depicted while in panels (e) and (f) median values of anti-inflammatory cytokines IL-10 and IL-1RA are shown ( per group). Panels (g–l) depict median ± interquartile range of area under curve (AUC) of the respective cytokines ( per group). values calculated using Mann-Whitney tests.