Gamma-Irradiated Bacille Calmette-Guérin Vaccination Does Not Modulate the Innate Immune Response during Experimental Human Endotoxemia in Adult Males

Figure 4

Production of IFN-gamma, TNF-α, and IL-1β by peripheral blood mononuclear cells stimulated ex vivo with Mycobacterium tuberculosis (MTB), LPS, Staphylococcus aureus (SA), and Candida albicans (CA) of subjects vaccinated with gamma-irradiated BCG or placebo. Data expressed as median and interquartile range of the fold change compared with day 1 (before vaccination) ( per group). values calculated using repeated measures two-way analysis of variance (ANOVA, time and interaction terms) on log-transformed data. Day 6 was the endotoxemia experiment day.