Research Article
A Novel PET Imaging Using 64Cu-Labeled Monoclonal Antibody against Mesothelin Commonly Expressed on Cancer Cells
Figure 3
In vivo and ex vivo NIR optical imaging by Alexa Fluor 750-labeled 11-25 mAb. (a) Alexa Fluor 750-labeled 11-25 mAb (90 μg/mouse) was administered to mice bearing BxPC-3 and PANC-1 intravenously. Alexa Fluor 750 fluorescence was then monitored by IVIS-200 imaging system 24, 48, and 72 hours after the injection. The minimum and maximum values of the photon gage are shown under each photograph. (b) 24 hours after administration of Alexa Fluor 750-labeled 11-25 mAb, tumors were dissected from mice and ex vivo fluorescence images were taken.
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