The Effect of Bacteriophage Preparations on Intracellular Killing of Bacteria by Phagocytes

Table 1

Intracellular killing of nonpathogenic and pathogenic strains compared to control.

Bacteria	Tested group of patients		Mean IKB by PMNs ± [%]		Mean IKB by PBMCs ± [%]
E. coli B	Control	39	87.0 ± 8.1	39	86.8 ± 8.8
	Before therapy	51	69.0 ± 13.0	51	69.2 ± 10.6
	During therapy	44	71.0 ± 10.2	44	71.4 ± 10.6
	After therapy	33	71.0 ± 12.9	33	76.0 ± 12.4
E. coli	Control	23	85.8 ± 7.5	23	85.7 ± 7.7
	Before therapy	7	72.6 ± 8.1	7	71.0 ± 12.2
	During therapy	6	75.4 ± 9.1	6	75.9 ± 12.7
	After therapy	5	75.8 ± 15.3	5	72.5 ± 17.3
E. faecalis	Control	25	88.0 ± 7.8	25	84.4 ± 7.2
	Before therapy	7	73.0 ± 11.5	7	73.2 ± 8.5
	During therapy	7	65.0 ± 16.5	7	66.8 ± 15.3
	After therapy	4	72.0 ± 5.6	4	75.9 ± 8.6
P. aeruginosa	Control	25	88.0 ± 6.5	25	87.9 ± 7.5
	Before therapy	11	71.5 ± 11.4	11	67.8 ± 13.7
	During therapy	10	72.4 ± 6.3	10	73.1 ± 8.7
	After therapy	7	69.5 ± 7.7	7	70.6 ± 6.1
S. aureus	Control	25	88.0 ± 6.7	25	88.3 ± 7.4
	Before therapy	23	74.0 ± 8.6	23	71.9 ± 8.5
	During therapy	18	70.10 ± 10.2	18	71.7 ± 11.4
	After therapy	14	70.80 ± 11.6	14	74.2 ± 9.6

The statistically significant difference between tested group and control (Mann-Whitney test).