SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis

Figure 7

Colocalization of SP140L with endogenous SP100 and PML in HeLa cells. (a–c) Ectopically expressed SP140L does not colocalize with endogenous PML. (d–f) Ectopically expressed SP140L colocalizes with endogenous SP100. (g) Cytofluorograms together with Pearson’s correlation coefficients for the overlap of red and green pixel intensities correspond to the images on their left. The proteins were detected with polyclonal anti-Myc (SP140L) and monoclonal anti-SP100 and anti-PML antibodies. Scale bar: 5 μm.