Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis

Figure 3

Quantification of MOG-specific B cell frequencies in MS patients according to disease activity and MS forms. (a) RR patients were classified according to disease state, for example, relapse or remission. We analysed the difference in MOG-BBR frequencies for patients in relapse () and patients in clinical remission () versus HI () (), Kruskal-Wallis test. No difference between patients in relapse and patients with clinical remission was observed (ns, ). (b) Eight patients with secondary progressive (SP) forms were included and compared to RR patients and HI. There was a statistically significant difference between SPMS patients and RR MS patients () but not between SPMS patients and HI (), Kruskal-Wallis test.

(a)

(b)