Estimation of the Impact of Meningococcal Serogroup C Universal Vaccination in Italy and Suggestions for the Multicomponent Serogroup B Vaccine Introduction

Table 3

Annual incidence rates per 100,000 Rate Ratios (RRs) and 95% CIs of IMD between the prevaccination and the postvaccination period in the Puglia region, within 2001–2013, by class of age.

Class of age	2001–2005		2006–2013
		Rate per 100,000		Rate per 100,000	RR (95% CI)
<1 year	1	2.48	1	2.7	1.1 (0.1–17.1)
1–4 years	3	1.82	1.7	1.1	0.6 (0.1–3.9)
5–9 years	2.2	1.01	1.3	0.6	0.6 (0.1–5.5)
10–14 years	1.8	0.75	1	0.5	0.6 (0.1–7)
15–19 years	2.2	0.86	1.3	0.6	0.6 (0.1–5.5)
20–24 years	2.4	0.84	2.7	1.1	1.2 (0.2–7.2)
25–49 years	3.4	0.23	1.2	0.1	0.3 (0.1–2.8)
≥50 years	4.6	0.34	4.5	0.3	0.9 (0.2–3.3)
Total	20.6	0.51	14.7	0.4	0.7 (0.4–1.4)

Pool of cases from the three sources’ linkage.