FoxP3 Tregs Response to Sublingual Allergen Specific Immunotherapy in Children Depends on the Manifestation of Allergy
Table 1
Demographic and clinical characteristics of children with allergy before and one year after ASIT.
Before ASIT
After ASIT
Number
17
15
Males
15
15
Females
2
0
Age (mean ±SD years)
7.9 ± 2.65
8.9 ± 2.86
Clinical symptoms
Group 1
8
9
Group 2
9
6
WBC (average ±SD cells/µL)
7817 ± 2427.4
6646 ± 1482.7
Median
8300
6100
Lymphocytes (average ±SD cells/µL)
3247 ± 982.4
2827 ± 677.7
Median
3300
2700
Lymphocytes (average ±SD %)
41.7 ± 11.62
43.0 ± 5.89
Median
43
42
Eosinophils (average ±SD cells/µL)
347 ± 373.3
304 ± 109,1
Median
277
324
Eosinophils (average ±SD %)
4.6 ± 3.61
4.7 ± 1.84
Median
3.8
4.1
sIgE (kU/L, scale 0–6)
>3 class
Group 1: patients with respiratory allergy: allergic rhinitis (AR), allergic conjunctivitis (AC), and asthma (CA). Group 2: patients with respiratory allergy and food allergy (FA) or atopic dermatitis (AD).