Research Article

FoxP3 Tregs Response to Sublingual Allergen Specific Immunotherapy in Children Depends on the Manifestation of Allergy

Table 1

Demographic and clinical characteristics of children with allergy before and one year after ASIT.

Before ASITAfter ASIT

Number1715
Males1515
Females20
Age (mean ±SD years)7.9 ± 2.658.9 ± 2.86
Clinical symptoms
 Group 189
 Group 296
WBC (average ±SD cells/µL)7817 ± 2427.46646 ± 1482.7
 Median83006100
Lymphocytes (average ±SD cells/µL)3247 ± 982.42827 ± 677.7
 Median33002700
Lymphocytes (average ±SD %)41.7 ± 11.6243.0 ± 5.89
 Median4342
Eosinophils (average ±SD cells/µL)347 ± 373.3304 ± 109,1
 Median277324
Eosinophils (average ±SD %)4.6 ± 3.614.7 ± 1.84
 Median3.84.1
sIgE (kU/L, scale 0–6) >3 class

Group 1: patients with respiratory allergy: allergic rhinitis (AR), allergic conjunctivitis (AC), and asthma (CA).
Group 2: patients with respiratory allergy and food allergy (FA) or atopic dermatitis (AD).