Comparative Immunogenicity in Rabbits of the Polypeptides Encoded by the 5′ Terminus of Hepatitis C Virus RNA

Table 1

A panel of overlapping peptides derived from HCV core and F-protein used in the tests of humoral and cellular immune response. First and last amino acid position are given according to HCV AD78 isolate genotype 1b (GenBank accession number AJ132996 [30, 36]).

Protein	Amino acid positions	Amino acid sequence
HCV core	1–35	MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVY
	21–55	DVKFPGGGQIVGGGVYLLPRRGPRLGVRATRKTSER
	41–75	GPRLGVRATRKTSERSQPRGRRQPIPKARRPEGRT
	61–95	RRQPIPKARRPEGRTWAQPGYPWPLYGNEGMGWAG
	81–115	YPWPLYGNEGMGWAGWLLSPRGSRPSWGPNDPRRR
	101–135	RGSRPSWGPNDPRRRSRNLGKVIDTLTCGFADLMG
	121–155	KVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGV
	161–195	GVNYATGNLPGCSFSILLALLSCLTTIPASAYEVR
	1–18	MSTIPKPQRKTKRNTNRR
	13–33	RNTNRRPQDVKFPGGGQIVGG
	34–42	VYLLPRRGP
	67–81	KARRPEGRTWAQPGY
	129–145	GFADLMGYIPLVGAPLG
	141–160	GAPLGGAARALAHGVRVLED
F-protein	30–49	SLAEFTCCRAGAPGWACARL
	45–64	ACARLGRLPSGRNLVEGDNL
	60–79	EGDNLSPRLAIPRAGPGLSL
	75–94	PGLSLGTLGPSMAMRAWGGQ
	90–109	AWGGQDGSCHPVALGLVGAP