Statins Increase the Frequency of Circulating CD4⁺FOXP3⁺ Regulatory T Cells in Healthy Individuals

Figure 3

Treg from statins-treated individuals have lower Ki67 expression. Cell cycling was evaluated by the expression of Ki-67 by CD4⁺FOXP3⁺ Treg cells (a) and total CD4⁺ T cells from peripheral blood of healthy donors treated with statins (b). Median, interquartile range (IQR), and values are shown in the graph; difference between days was tested by Wilcoxon signed-rank test.

(a)

(b)