Distribution of Peripheral Lymphocyte Populations in Primary Sjögren’s Syndrome Patients

Table 2

Distribution of lymphocyte populations in peripheral blood of pSS patients and controls.

Patients	^1I-controls	^2II-pSS Abs^−	^3III-pSS Abs^+
				I-II	I-III	II-III
Main lymphocyte populations
CD3^+ T cells
%^4	75.36 ± 6.93	72.16 ± 9.81	73.03 ± 8.47	NS	NS	NS
A. count^#	2530 ± 811.0	2154 ± 1133	1868 ± 1052	0.027	0.0002	NS
CD4^+ T cells
%^4	49.33 ± 9.12	46.20 ± 8.49	39.37 ± 12.39	NS	0.0036	0.036
A. count^#	1688 ± 654.9	1391 ± 804.3	1089 ± 975.4	0.015	<0.0001	0.01
CD8^+ T cells
%^4	26.73 ± 7.29	26.25 ± 8.82	29.87 ± 11.64	NS	NS	NS
A. count^#	939 ± 326.4	760.5 ± 433.5	690.2 ± 259.6	0.014	0.006	NS
B cells
%^4	11.86 ± 4.43	13.82 ± 9.13	14.52 ± 5.15	NS	0.045	NS
A. count^#	401.3 ± 216.5	351.2 ± 197.8	393.5 ± 294.1	NS	NS	NS
NK
%^4	12.19 ± 5.67	12.99 ± 6.84	12.10 ± 6.05	NS	NS	NS
A. count^#	415.4 ± 186.7	365.7 ± 210.7	306.1 ± 201.7	NS	0.036	NS
NKT
%^4	6.79 ± 4.26	8.44 ± 8.51	6.36 ± 5.86	NS	NS	NS
A. count^#	223.4 ± 132.0	206.7 ± 168.6	137.7 ± 127.1	NS	0.009	NS

I group: healthy controls; ²II group: pSS patients without anti-SSA/SSB; ³III group: pSS patients with anti-SSA and/or anti-SSB; %⁴: proportion of all CD4⁺ lymphocytes; A. count^#: absolute count of cells in 1 μL of blood. ^*Mann-Whitney test. NS: not significant.