Distribution of Peripheral Lymphocyte Populations in Primary Sjögren’s Syndrome Patients
Table 2
Distribution of lymphocyte populations in peripheral blood of pSS patients and controls.
Patients
1I-controls
2II-pSS Abs−
3III-pSS Abs+
I-II
I-III
II-III
Main lymphocyte populations
CD3+ T cells
%4
75.36 ± 6.93
72.16 ± 9.81
73.03 ± 8.47
NS
NS
NS
A. count#
2530 ± 811.0
2154 ± 1133
1868 ± 1052
0.027
0.0002
NS
CD4+ T cells
%4
49.33 ± 9.12
46.20 ± 8.49
39.37 ± 12.39
NS
0.0036
0.036
A. count#
1688 ± 654.9
1391 ± 804.3
1089 ± 975.4
0.015
<0.0001
0.01
CD8+ T cells
%4
26.73 ± 7.29
26.25 ± 8.82
29.87 ± 11.64
NS
NS
NS
A. count#
939 ± 326.4
760.5 ± 433.5
690.2 ± 259.6
0.014
0.006
NS
B cells
%4
11.86 ± 4.43
13.82 ± 9.13
14.52 ± 5.15
NS
0.045
NS
A. count#
401.3 ± 216.5
351.2 ± 197.8
393.5 ± 294.1
NS
NS
NS
NK
%4
12.19 ± 5.67
12.99 ± 6.84
12.10 ± 6.05
NS
NS
NS
A. count#
415.4 ± 186.7
365.7 ± 210.7
306.1 ± 201.7
NS
0.036
NS
NKT
%4
6.79 ± 4.26
8.44 ± 8.51
6.36 ± 5.86
NS
NS
NS
A. count#
223.4 ± 132.0
206.7 ± 168.6
137.7 ± 127.1
NS
0.009
NS
I group: healthy controls; 2II group: pSS patients without anti-SSA/SSB; 3III group: pSS patients with anti-SSA and/or anti-SSB; %4: proportion of all CD4+ lymphocytes; A. count#: absolute count of cells in 1 μL of blood. *Mann-Whitney test. NS: not significant.