Research Article
Cyclic AMP-Responsive Element Modulator α Polymorphisms Are Potential Genetic Risks for Systemic Lupus Erythematosus
Table 2
Allele analysis of CREMα tagSNPs in SLE association.
| | SNPs | Allele | Allelic frequencies (cases versus controls) | MAF (cases versus controls) | OR (95% CI) | values |
| | rs1057108 | G/T | 542/1216, 444/1160 | 0.308, 0.277 | 1.165 (1.003–1.152) | 0.049 | | rs2295415 | G/A | 343/1275, 265/1225 | 0.212, 0.178 | 1.244 (1.040–1.478) | 0.019 | | rs11592925 | T/C | 169/1591, 159/1447 | 0.096, 0.099 | 0.967 (0.770–1.214) | 0.772 | | rs1148247 | A/G | 574/1054, 536/948 | 0.353, 0.361 | 0.963 (0.832-1.116) | 0.626 |
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CREMα: cyclic AMP-responsive element modulator α; SNPs: single-nucleotide polymorphisms; MAF: minor allele frequency; OR: odds ratio; CI: confidence interval.
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