Sex Hormones in Allergic Conjunctivitis: Altered Levels of Circulating Androgens and Estrogens in Children and Adolescents with Vernal Keratoconjunctivitis
Table 1
Clinical characteristics of patients included in this study.
Total
Prepuberty
Early puberty
Late puberty
Patients
25
12
7
6
Atopic associated diseases ()
Rhinitis
2
0
2
0
Asthma
5
2
1
2
Atopic dermatitis
2
2
0
0
Atopic dermatitis and asthma
4
1
1
2
None
12
7
3
2
Skin prick test ()
Positive
14
7
3
4
Negative
11
5
4
2
Total IgE (U/mL)
215 ± 257
323 ± 347
261 ± 189
111 ± 76
Duration of VKC (years)
Mean ± SD
5.6 ± 3.4
3 ± 1.4
6.1 ± 2.2
10 ± 2.6
VKC type ()
Tarsal
22
11
7
4
Limbal
3
1
0
2
Mixed
0
0
0
0
VKC course
Seasonal
14
6
5
3
Perennial
11
6
2
3
VKC grade
0—quiescent
6
0
0
6
1—mild
2
2
0
0
2—moderate
9
6
3
0
3—severe
4
1
3
0
4—very severe
4
3
1
0
SD: standard deviation; VKC: vernal keratoconjunctivitis.