Research Article
Peripheral Blood Mononuclear Cell Gene Expression Remains Broadly Altered Years after Successful Interferon-Based Hepatitis C Virus Treatment
Table 2
Genes with significantly different (
) upregulation in both SVR and NR when compared to SC.
| Gene ID | SC mean count | SVR mean count | NR mean count | Fold change SVR/SC | Fold change NR/SC | Fold change SVR/NR | value SC v SVR | value SC v NR | value SVR v NR |
| MAP2K1 | 938 | 1205 | 1197 | 1.3 | 1.3 | 1 | | | 0.793 | FOS | 19984 | 61310 | 62471 | 3 | 3.1 | −1.0 | | | 0.834 | CEBPB | 1571 | 3033 | 2873 | 1.9 | 1.8 | 1.1 | | | 0.608 | RAC1 | 809 | 1006 | 1083 | 1.2 | 1.3 | −1.1 | | | 0.200 | HLA-DRA | 19648 | 27320 | 24871 | 1.4 | 1.3 | 1.1 | | | 0.085 | MYD88 | 1868 | 2288 | 3060 | 1.2 | 1.6 | −1.3 | | | 0.0017 | GNB1 | 5733 | 6570 | 6537 | 1.2 | 1.1 | 1.0 | | | 0.912 | RHOA | 2575 | 3159 | 3562 | 1.2 | 1.4 | −1.1 | | | 0.048 | CFD | 199 | 338 | 364 | 1.7 | 1.8 | −1.1 | | | 0.474 | IL10 | 1 | 20 | 13 | 12.9 | 8.2 | 1.6 | | | 0.110 | CCR1 | 503 | 845 | 1048 | 1.7 | 2.1 | −1.2 | | | 0.109 | IL1RN | 389 | 625 | 852 | 1.6 | 2.19 | −1.36 | | | 0.058 |
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