Anti-Phosphatidylserine/Prothrombin Antibodies Are Associated with Adverse Pregnancy Outcomes

Table 5

Diagnostic accuracy of aPL for pregnancy loss as defined by APS classification criteria.

	Pregnancy loss defined by APS criteria [1]
	AUC	OR [95 %CI]
LA	0.541	0.6 [0.6-0.7]	ns
aCL	0.549	7.4 [1.6–34.5]	0.010
IgG	0.541	12.1 [1.5–97.5]	0.019
IgM	0.514	2.8 [0.3–26.9]	ns
anti-β2GPI	0.499	1.5 [0.5–4.6]	ns
IgG	0.492	1.2 [0.4–3.9]	ns
IgM	0.514	0.7 [0.6-0.7]	ns
aPS/PT	0.549	7.4 [1.5–35.2]	0.012
IgG	0.535	11.0 [1.3–91.5]	0.012
IgM	0.525	9.0 [1.0–78.9]	0.047

AUC: area under the curve, aCL: anticardiolipin antibody, anti-β₂GPI: antibodies against β₂-glycoprotein I, aPS/PT: anti-phosphatidylserine/prothrombin antibodies, CI: confidence interval, LA: lupus anticoagulant, ns: not significant, and OR: odds ratio.