Increased Performances of the Biological Diagnosis of the Antiphospholipid Syndrome by the Use of a Multiplex Assay

Table 2

Performances of the assays according to the clinical scores used.

Assay	Score used	AUC	95% CI	Sensitivity/specificity (%) at optimal cut-off [U]
Cardio FIDIS	2-3	0.795	0.737–0.846	77/73 8
	3	0.917^*	0.873–0.949^*	100/73 9
Cardiolisa	2-3	0.762	0.702–0.816	65/79 30
	3	0.851^*	0.798–0.895^*	88/69 21
B2GP1 FIDIS	2-3	0.863^**	0.811–0.905^**	72/86 1
	3	0.906	0.861–0.941	89/93 4
B2GP1 ELISA	2-3	0.715^**	0.652–0.773^**	59/83 120
	3	0.890	0.843–0.928	89/87 165
Factor II FIDIS	2-3	0.719	0.656–0.776	41/95 5
	3	0.767	0.707–0.820	50/97 7
Lupus anticoagulant	2-3	0.785	0.672–0.898	63/94
	3	0.731	0.621–0.841	48/99

Significative difference between cardio FIDIS and ELISA () (^*) and B2GP1 FIDIS and ELISA () (^**); AUC: area under the curve.