Research Article

Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction

Table 1

Characteristics of 225 (alemtuzumab) and 205 (basiliximab) recipients and solitary kidney transplants.

CharacteristicAlemtuzumab ()Basiliximab () value

Male gender (, %)140 (62.22%)136 (66.34%)0.495
Age in years (mean ± SD)48.46 ± 12.3759.57 ± 13.16<0.0001
Cause of renal failure (, %)
 Glomerulonephritis71 (31.55%)68 (33.17%)0.533
 Diabetes mellitus61 (27.12%)58 (28.29%)0.512
 Polycystic kidney disease22 (9.78%)23 (11.22%)0.856
 Others71 (31.55%)59 (28.78%)0.051
prior kidney transplantation (, %)41 (18.22%) 17 (8.29%)0.002
PRA+ recipients (, %) 143 (63.56%)131 (63.90%)0.021
PRA at KTx (in %, mean ± SD)22.93 ± 26.9915.65 ± 4.250.189
HLA-A mismatch148 (65.78%)152 (74.14%)0.199
HLA-B mismatch180 (80%)172 (83.90%)0.019
HLA-DR mismatch169 (75.11%)166 (80.97%)0.457
CMV-IgG+ (, %) 141 (62.67%) 145 (70.73%) 0.135
CMV mismatch (R−/D+) (, %) 42 (18.67%)34 (16.59%)0.061
Lymphocyte count before Tx (in %, mean ± SD) 22.8 ± 9.4123.77 ± 10.420.412