Research Article
Scaffolded Antigens in Yeast Cell Particle Vaccines Provide Protection against Systemic Polyoma Virus Infection
Table 2
Anti-GFP IgG titers, defined as reciprocals of dilutions giving a response twofold above background.
| Vaccine dosage | Bleed 1 | Bleed 2 | Bleed 3 | Bleed 4 | Bleed 5 |
| (A) Subcutaneous | 400–1600 | 800–6,400 |
3,200–12,8000 | 1,600–25,600 | 3,400–102,000 | Average | 800 | 3,000 | 6,000 | 10,000 | 25,000 | (B) Low dose oral | <200 | 200–800 | 400–6400 | 400–3200 | 200–3200 | Average | <200 | 400 | 2200 | 1200 | 1600 | (C) High dose oral | <200 | 200–800 | 200–12,800 | 400–12,800 | 400–12,800 | Average | <200 | 500 | 3,500 | 6,700 | 6,700 |
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