Research Article

Preexisting Antibodies to an F(ab′)2 Antibody Therapeutic and Novel Method for Immunogenicity Assessment

Figure 3

Comparative reactivity of cynomolgus monkey serum samples with anti-DLL4 Fab or anti-DLL4 F(ab′)2 directly coated on a well (direct binding format). More sample reactivity is observed with the F(ab′)2 coat.