Delta Procalcitonin Is a Better Indicator of Infection Than Absolute Procalcitonin Values in Critically Ill Patients: A Prospective Observational Study
Table 4
The predictive value of the absolute values, percentage, and delta changes of PCT, CRP, temperature, and WBC count for infection in the total cohort.
Absolute value
Percentage changes
Absolute value changes
AUC
95% CI
value
AUC
95% CI
value
AUC
95% CI
value
Total
PCT
0.64
0.52–0.76
0.022
0.77
0.66–0.87
<0.001
0.85
0.78–0.92
<0.001
CRP
0.60
0.47–0.72
0.103
0.54
0.41–0.66
0.530
0.54
0.42–0.65
0.536
BT
0.52
0.39–0.63
0.804
0.56
0.44–0.68
0.300
0.56
0.44–0.68
0.322
WBC
0.60
0.48–0.70
0.125
0.51
0.40–0.61
0.852
0.51
0.39–0.61
0.924
Medical
PCT
0.67
0.54–0.80
0.016
0.76
0.63–0.88
<0.001
0.83
0.73–0.92
<0.001
CRP
0.58
0.44–0.72
0.248
0.57
0.42–0.70
0.359
0.57
0.44–0.70
0.306
BT
0.51
0.37–0.64
0.858
0.64
0.50–0.77
0.055
0.64
0.49–0.77
0.060
WBC
0.57
0.44–0.70
0.329
0.56
0.43–0.68
0.441
0.57
0.43–0.69
0.365
Surgical
PCT
0.78
0.58–0.97
0.025
0.80
0.59–1.00
0.014
0.94
0.85–1.00
<0.001
CRP
0.56
0.23–0.87
0.654
0.56
0.29–0.81
0.654
0.54
0.31–0.76
0.749
BT
0.52
0.22–0.80
0.898
0.63
0.39–0.85
0.306
0.63
0.39–0.86
0.296
WBC
0.63
0.44–0.82
0.277
0.67
0.47–0.86
0.166
0.71
0.49–0.90
0.108
AUC: area under the ROC curve, CI: confidence interval, PCT: procalcitonin, CRP: C-reactive protein, BT: body temperature, and WBC: white blood cell count.
