Prophylactic Chronic Zinc Administration Increases Neuroinflammation in a Hypoxia-Ischemia Model

Figure 5

Effect of the chronic prophylactic administration of zinc on levels of zinc and stress nitrosative markers. CZn15 d, rats with chronic administration of zinc; Zn15 d+CCAO 8 h, rats with chronic administration of zinc before CCAO and evaluations at 8 h after reperfusion; Zn15 d+CCAO 7 d, rats with chronic administration of zinc before CCAO and evaluations at 7 days after reperfusion. Values are represented as the percentage with respect to untreated control. Each value represents the mean ± SEM of 5 independent experiments made in triplicate. different from untreated rats (Student’s -test). The significance was established at .

(a)

(b)

(c)

(d)