Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro

Figure 2

Cells with BCG-mycobacteria in the cultures of (a) bone marrow macrophages and (b) peritoneal macrophages following infection with the BCG vaccine in vitro and after culture for several hours. Acid-fast BCG-mycobacteria stained by the ZN method. The scale bars are 10 μm each. Infected macrophages and neutrophils are indicated by the black and red arrows, respectively. Nonacid-fast BCG-mycobacteria (blue color) eliminated by macrophages are indicated by the black snowflakes. Abbreviations as in Figure 1.

(a)

(b)