Review Article

How Neutrophil Extracellular Traps Become Visible

Table 2

Definition of Latin terms used in this paper for the detection of NETs in viable or fixed samples and individuals.

Latin termTranslationDefinition used in this reviewExamples

In vivoWithin the living organismEffects analyzed on whole, living organismsDetection of NETs in a living animal after an infection with bacteria

In situIn the natural, correct positionEffects analyzed on whole or partial organisms that are dead Detection of NETs in histological samples derived from infected animals

Ex vivoOut of the living organismEffects analyzed on live isolated cells or biopsies with a minimum of changes of the natural conditions (tissue or body fluid) Detection of NETs in body fluids (cytospin) or in tissue without fixation directly after isolation from viable organism

In vitroIn a test tubeEffects tested under laboratory conditions in test tubes, for example, Petri dishesDetection of NET formation in response to pathogens or chemicals by purified blood-derived neutrophils in tissue culture plates

IntravitalOccurring during lifeVisualization of an event in the living organisms by microscopy, same as in vivoSee in vivo