A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis

Figure 2

Expression of receptors in CFS/ME, MS, and nonfatigued controls. (a) CD49d/CD29 was reduced in EM subsets of CD8+ T cells in the CFS/ME patients but elevated in EMRA subsets of CD8+ T cells in MS patients compared to controls. (b) CD127 expression was reduced on naïve, EM, and EMRA subsets of CD8+ T cells in the CFS/ME patients but not CM subsets as CD127+ CD8+ T cells were evaluated in MS patients compared with controls. MS patients also demonstrated elevated naïve CD8 T cells compared with controls. Data is represented as median ± SEM, where represents (EM: effector memory, EMRA: effector memory RA, and CM: central memory).

(a)

(b)