Research Article

Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome

Table 3

The 14 autoantibodies building the classifier.

ā€‰Antibody directed against the following proteinsUltimate ORF ID/catalog number

1Retinoic acid receptor-beta (RARB) transcript variant 2Hs~Ref:NM_016152.2~uORF:IOH36705~RFU:23189.6
2Phosphoglucomutase 2-like 1 (PGM2L1)Hs~MGC:BC059360.1~uORF:IOH29131~RFU:29573.42
3Hepatitis B virus x interacting protein (HBXIP)Hs~Ref:NM_006402.2~uORF:IOH40860~RFU:21469.91
4Hypothetical protein MGC24103 (MGC24103)Hs~MGC:NM_152576.1~uORF:IOH23047~RFU:19377.96
5cAMP responsive element modulator (CREM), transcript variant 20, mRNAHs~Ref:NM_183012.1~uORF:IOH53457~RFU:0
6Transient receptor potential cation channel subfamily M member 3Hs~MGC:BC022454.2~uORF:IOH10977~RFU:4933.46
74-Hydroxyphenylpyruvate dioxygenaseHs~Ref:NM_002150.1~uORF:IOH14718~RFU:30044.88
8Chromosome 20 open reading frame 71 (C20orf71)Hs~MGC:BC066354.1~uORF:IOH40076~RFU:14763.08
9TNFSF10/APO2L/TRAIL/CD253 protein (native)Hs~Ref:NP_003801.1~CAT_10409-HNAE-25~RFU:28.23
10Kv channel interacting protein 4 (KCNIP4), transcript variant 1Hs~Ref:NM_025221.4~uORF:IOH21934~RFU:27826.87
11Exosome component 5 (EXOSC5)Hs~MGC:BC007742.1~uORF:IOH6517~RFU:29914.87
12Golgi SNAP receptor complex member 1 (GOSR1), transcript variant 1Hs~Ref:NM_004871.2~uORF:IOH45920~RFU:29968.08
13Chromosome 18 open reading frame 32 (C18orf32)Hs~MGC:BC022357.1~uORF:IOH14149~RFU:28760.06
14Proline-rich transmembrane protein 2 (PRRT2)Hs~MGC:BC053594.1~uORF:IOH28968~RFU:10273.9