Review Article
Porcine to Human Heart Transplantation: Is Clinical Application Now Appropriate?
Table 2
Anti-CD40 antibodies in clinical development.
| | Antibody | Company | Status | Trial ID |
| | SGN-40 | Seattle Genetics Inc. | Phase 1 multiple myeloma
Phase 2 B-cell lymphoma
Phase 1/2 chronic lymphocytic leukemia | NCT00079716
NCT00435916
NCT00283101 |
| | ASKP 1240 | Astellas | Phase 2 renal Tx phase 2 plaque
Psoriasis | NCT01780844
NCT01585233 |
| | HCD122 | Novartis | Phase 1, chronic lymphocytic leukemia
Phase 2 multiple myeloma
Phase 2 follicular lymphoma
Phase 1/2 Hodgkin’s and non-Hodgkin’s lymphoma | NCT00108108
NCT00231166
NCT01275209
NCT00670592 |
| | Chi Lob 7/4 | Cancer Res UK | Phase 1 cancer malignancies | NCT01561911 | | BG9588 | NIDDK | Phase 2 renal Tx | NCT00001857 | | | NIAMS | Phase 2 lupus nephritis | NCT00001789 |
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