Immunomodulatory Effects of Taiwanese Neolitsea Species on Th1 and Th2 Functionality

Figure 1

The effects of Taiwanese Neolitsea plants on T-cell viability and activation. Splenocytes (5 × 10⁶) were treated with vehicle control (VH, 0.05% DMSO) and/or various crude extracts of Neolitsea plants (10 μg/mL) followed by ConA treatment for 48 h. (a) The cell viability was determined using an MTT assay and the level of (b) IL-2 in the supernatants was quantified by ELISA. The viability and IL-2 level of the VH-treated group was shown as 100%. L, S, and R were represented as leaf, stem, and root parts of different plants. The effects of N. aciculata, N. aciculata var. variabillima, N. acuminatissima, N. buisanensis, N. daibuensis, N. hiiranensis, N. konishii, N. parvigemma, N. sericea var. aurata, and N. villosa on (a) cell viability and (b) IL-2 production were shown from top to bottom, respectively. Data were expressed as the mean ± SE of triplicated cultures. Results were pooled from three independent experiments. , compared to the VH group.

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