CD80 Expressed by CD8⁺ T Cells Contributes to PD-L1-Induced Apoptosis of Activated CD8⁺ T Cells

Figure 2

CD80-KO and WT CD8⁺ T cells express equivalent levels of cell surface markers of activation after ConA activation. WT and CD80-KO cells were activated with ConA, then harvested for analysis. Cells were then analyzed by flow cytometry. (a) Histograms are of live CD8⁺ cells and representative of 3 separate experiments. (b) Mean fluorescent intensity (MFI) for PD-1 and CD86 (, ±SD, not significant).

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(b)