Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers

Figure 1

Comparison of different circulating myeloid cell subsets between HD and cancer patients. Peripheral blood from 21 HD, 30 PBC patients, and 20 CRC patients was stained for myeloid cell markers. Scatter plots show the mean percentages ± SEM of CD33⁺ cells gated on all cells (a), CD33⁺CD11b⁺ cells gated on CD33⁺ cells (b), CD33⁺ CD11b⁺HLA-DR^−/low cells (c), CD33⁺CD11b⁺HLA-DR^−/lowCD14⁺ MMC (d), CD33⁺CD11b⁺ HLA-DR^−/lowCD15⁺ GMC (e), ARG1 expression in MMC (f), ARG1 expression in GMC (g), CD33⁺ CD11b⁺HLA-DR⁺ APC (h), and CD33⁺ CD11b⁺HLA-DR^−/lowCD14⁻CD15⁻IMC (i) gated on the respective parent population in the three study groups. indicates value of ≤0.05, indicates value of ≤0.01, and indicates value of ≤0.001.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)