Research Article
Inflammatory Cytokine Pattern Is Sex-Dependent in Mouse Cutaneous Melanoma Experimental Model
Table 1
Cytokine/chemokine panel analyzed by Luminex-based cytokine bead array.
| Function | Name | Cell source |
| Proinflammatory cytokines | IL-1-beta, IFN-gamma | Lymphocytes | IL-12 (p70) | Monocytes/macrophages and B cells | TNF-alpha | Macrophages |
| Anti-inflammatory cytokines | IL-10 | Mainly monocytes |
| Pleiotropic cytokines | GM-CSF | Macrophages, T cells, mast cells, natural killer cells, endothelial cells, and fibroblasts | IL-6 | Mainly T cells and macrophages |
| Chemokines | MCP-1 | Primarily monocytes, macrophages, and dendritic cells | MIP-1 | Memory CD8+ T cells | KC | Macrophages, neutrophils, epithelial cells, and melanoma cells |
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