Regulation of Leukocyte Recruitment to the Spleen and Peritoneal Cavity during Pristane-Induced Inflammation

Figure 5

The absence of TNFR1/2 inhibited the recruitment of splenic neutrophils, macrophages, and dendritic cells in response to pristane treatment. (a, b) TNFR1/2^−/− mice and WT mice were injected with 300 μL (8.3 × 10⁻⁴ mol) of pristane and sacrificed at three weeks thereafter. Total number of cells and the number of each cell type were calculated. (c, d) Total number of cells and the number of each cell type in the PC were also analyzed. The difference between WT and TNFR1/2^−/− mice is shown. Data represent two independent experiments. .

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