Distinct Profiles of CD163-Positive Macrophages in Idiopathic Interstitial Pneumonias

Figure 1

Immunohistochemical analysis of CD68 expression in IIPs. (a) CD68⁺ macrophages (Brown) were scattered in the alveolar space of normal control lungs. Numerous CD68⁺ macrophages were observed in the alveolar space in IIPs, including IFF/UIP (b), NSIP (c), and COP (d). In the interstitium, CD68⁺ macrophages were observed in NSIP and COP, but barely detectable within the intraluminal fibrosis in COP. Resorcin-fuchsin and hematoxylin were used as counterstains. Scale bar, 200 μm.

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