Clinical Study
Host Immunological Effects of Partial Splenic Embolization in Patients with Liver Cirrhosis
Table 2
Changes of various parameters before and after 4 weeks of PSE.
| | Pre-PSE | Post-PSE | |
| Ammonia (mg/dl) | 82.1 ± 94 | 51.0 ± 43 | 0.1140 | Total bilirubin (g/dl) | 1.5 ± 0.9 | 1.6 ± 1.2 | 0.6130 | Direct bilirubin (g/dl) | 0.6 ± 0.5 | 0.7 ± 0.9 | 0.2650 | Albumin (mg/dl) | 3.2 ± 0.6 | 3.1 ± 0.6 | 0.1050 | AST (IU/l) | 52.1 ± 30 | 58.3 ± 44 | 0.3890 | ALT (IU/l) | 34.8 ± 27 | 32.5 ± 28 | 0.0890 | Total cholesterol (mg/dl) | 130.2 ± 30 | 127.4 ± 21 | 0.9650 | Blood urea nitrogen (mg/dl) | 16.6 ± 8 | 15.0 ± 6 | 0.1050 | Creatinine (mg/dl) | 0.8 ± 0.3 | 0.8 ± 0.2 | 0.1300 | Prothrombin time (%) | 65.8 ± 14 | 69.7 ± 13 | 0.013 | White blood cell (/mm3) | 2945.4 ± 1471 | 4704.6 ± 1730 | 0.001 | Segment (/mm3) | 1791.2 ± 954 | 2809.3 ± 912 | 0.009 | Lymphocyte (/mm3) | 607.2 ± 215 | 1038.0 ± 451 | 0.006 | Monocyte (/mm3) | 245.9 ± 70 | 440.9 ± 103 | 0.001 | Platelets (×104/mm3) | 4.32 ± 1.5 | 8.95 ± 5.0 | 0.001 | AFP (ng/ml) | 2561.3 ± 5704 | 19806.0 ± 39533 | 0.0679 | AFP-L3 (%) | 19.3 ± 22 | 26.2 ± 31 | 0.1088 | DCP (AU/ml) | 325.2 ± 677 | 364.5 ± 490 | 1.0000 | Child-Pugh score | 7.6 ± 1.9 | 7.4 ± 1.9 | 0.4174 |
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PSE: partial splenic embolization; AST: aspartate aminotransferase; ALT: alanine aminotransferase; AFP: alpha-fetoprotein; DCP: des-gamma carboxyprothrombin. Statistically different compared with Wilcoxon’s signed-rank sum test. |