Research Article
Fetal and Maternal Outcomes of Planned Pregnancy in Patients with Systemic Lupus Erythematosus: A Retrospective Multicenter Study
Table 2
Association of different characteristics during pregnancy with composite fetal APOs.
| | Characteristics | Total () | With fetal APOs () | Without fetal APOs () | value |
| | Clinical manifestation at any time (n, %) | | | | | | Flare during pregnancy | 52 (21.4) | 40 (46.5) | 12 (7.6) | <0.001 | | Active lupus nephritis | 45 (18.5) | 32 (37.2) | 13 (8.3) | <0.001 | | Thrombocytopenia | 23 (9.5) | 14 (16.3) | 9 (5.7) | 0.01 | | Leukopenia | 7 (2.9) | 4 (4.7) | 3 (1.9) | 0.2 | | Skin rash | 19 (7.8) | 9 (10.5) | 10 (6.4) | 0.3 | | Joint involvement | 18 (7.4) | 6 (7.0) | 12 (7.6) | 0.9 | | Serological profile at any time (n, %) | | | | | | Anti-dsDNA antibody positivity | 93 (38.3) | 34 (39.5) | 59 (37.6) | 0.8 | | Anti-Ro antibody positivity | 50 (20.6) | 19 (22.1) | 31 (19.8) | 0.7 | | Anti-La antibody positivity | 33 (13.6) | 12 (14.0) | 21 (13.4) | 1.0 | | LAC positivity | 19 (7.8) | 14 (16.3) | 5 (3.2) | <0.001 | | aCL IgG positivity | 25 (10.3) | 21 (24.4) | 4 (2.5) | <0.001 | | aCL IgM positivity | 13 (5.3) | 11 (12.8) | 2(1.3) | <0.001 | | Anti-beta2 GP1 positivity | 21 (8.6) | 7 (8.1) | 14 (8.9) | 0.8 | | Hypoalbuminemia | 66 (27.2) | 29 (33.7) | 37 (23.6) | 0.09 | | mg/dL | 40 (16.5) | 24 (27.9) | 16 (10.2) | <0.001 | | mg/dL | 51 (21.0) | 29 (33.7) | 22 (14.0) | <0.001 |
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