The Fate of Allogeneic Pancreatic Islets following Intraportal Transplantation: Challenges and Solutions

Figure 3

(a) The three-signal pattern of T lymphocytes activated in islet allotransplantation. Action targets and brief mechanisms are displayed. (b) Current immunosuppressive protocol commonly used in clinical islet transplantation associated with improved long-term islet allograft survival.

(a)

(b)