Research Article

The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China

Table 3

Comparison of the common drug causality between northern and southern China.

Northern China, n (%) ()Southern China, n (%) ()Total, n (%) ()

Antibiotics14 (30.4)35 (29.2)49 (29.5)
 Penicillins3 (6.5)9 (7.5)12 (7.2)
 Cephalosporins1 (2.2)6 (5.0)7 (4.2)
 Quinolones2 (4.3)4 (3.3)6 (3.6)
 Others8 (17.4)16 (13.3)24 (14.5)
Anticonvulsants13 (28.3)27 (22.5)40 (24.1)
 Carbamazepine9 (19.6)20 (16.7)29 (17.5)
 Lamotrigine2 (4.3)5 (4.2)7 (4.2)
 Others2 (4.3)2 (1.7)4 (2.4)
Nondrug1 (2.2)18 (15.0)19 (11.4)
Allopurinol2 (4.3)14 (11.7)16 (9.6)
Multiple drugs6 (13.0)4 (3.3)10 (6.0)
Herbal medication2 (4.3)7 (5.8)9 (5.4)
NSAIDs4 (8.7)4 (3.3)8 (4.8)
Others4 (8.7)11 (9.2)15 (9.0)

NSAIDs: nonsteroidal anti-inflammatory drugs.