Expression of PD-1 on CD4⁺ Tumor-Infiltrating Lymphocytes in Tumor Microenvironment Associated with Pathological Characteristics of Breast Cancer

Table 3

Correlation between CD4/PD-1 TILs and other molecules in breast cancer.

	CD4^+ TILs		CD4^+/PD1^+ TILs		CD4^+/PD1^− TILs
CK7, median (IQR)^∗		0.913		0.724		0.684
No	72 (94)		14 (81)		26 (31)
Yes	56 (76)		22 (44)		32 (52)
CK20, median (IQR)^∗		0.152		0.415		0.025
No	55 (84)		22 (43)		30 (45)
Yes	100 (53)		31 (55)		73 (46)
E-Cad, median (IQR)^∗		0.013		0.157		0.012
No	23 (28)		5 (25)		10 (11)
Yes	48 (63)		16 (32)		30 (34)
Ki-67, correlation coefficient^∗∗	0.20	0.023	0.29	0.001	0.09	0.296

^∗Wilcoxon test. ^∗∗Spearman correlation test.