Silicone-Induced Granuloma of Breast Implant Capsule (SIGBIC): Histopathology and Radiological Correlation

Figure 9

Histology of mixed SIGBIC associated with seroma of the same patient of Figure 8. (a) Optical microscopy. Prevalence of intracellular silicone, with light spheres that vary in size, located within histiocytes. (b) Immunohistochemistry. CD3 reaction. Prevalence of T lymphocyte, both in the germinal center (right image) and dispersed by the capsule (left image). (c) Immunohistochemistry. CD20 reaction shows B lymphocyte reaction (left figure), and CD68 shows histiocyte reaction (left image).

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