Hypocomplementemia as a Risk Factor for Organ Damage Accrual in Patients with Systemic Lupus Erythematosus

Table 4

Multivariate analysis of hypocomplementemia (HC) and anti-dsDNA Ab presence as a risk factor for SLICC-DI >0 at last visit by logistic (yes/no) and time dependent Cox regression (risk increase per episode of HC).

Risk factor	HC	HC + anti-dsDNA
Logistic regression	OR (CI)	OR (CI)
Unadjusted binary exposure	2.03 (0.78, 5.27)	4.42 (1.25, 15.64)
Unadjusted continuous exposure	1.07 (1.00, 1.14)	1.06 (0.98, 1.15)
Cox regression	OR (CI)	OR (CI)
Unadjusted binary exposure	2.06 (1.13, 3.74)	1.53 (0.82, 2.87)
Unadjusted continuous exposure	0.98 (0.95, 1.01)	0.99 (0.95, 1.03)
Age-adjusted binary exposure	2.38 (1.31, 4.35)	2.04 (1.05, 3.98)
Age-adjusted continuous exposure	0.97 (0.94, 1.00)	0.98 (0.94, 1.02)

Figures indicate odds ratios (ORs) with 95% CI.