Review Article

Receptors That Inhibit Macrophage Activation: Mechanisms and Signals of Regulation and Tolerance

Figure 1

Schematic representation of the structures of inhibitory receptors. All receptors belong to the superfamily of immunoglobulins. They have a single transmembrane portion and an intracellular tail, through which they associate with proteins or effector enzymes. The immunoglobulin domains are represented as blue ovals for receptors and red ovals for ligands.