Research Article
Development of Safe and Non-Self-Immunogenic Mucosal Adjuvant by Recombinant Fusion of Cholera Toxin A1 Subunit with Protein Transduction Domain
Figure 7
TCTA1T is not immunogenic. BALB/c mice were immunized three times with 2 μg of CT or 10 μg of TCTA1T by i.n. or i.d. routes. Sera were collected on day 14 after the last immunization. Levels of (a) CTA1- and (b) CT-specific IgG Abs in sera were determined by ELISA. The results are expressed as mean ± SD for the group (). ND stands for not detectable.
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