Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice

Figure 3

Presence of LPF antigens in the liver of LPF-infected A/J mice. (a) Liver sections from A/J mice were incubated with rabbit antileptospire immune serum. (b) Semiquantitative measurements of LPF antigens in the liver of infected A/J mice were performed in seven random fields of each section. Significant differences are indicated as when , , and . A/J^-/-: C5-deficient mice, PBS (), 3 dpi (), 6 dpi (); A/J C5^+/+: congenic C5-sufficient mice PBS (), 3 dpi (), 6 dpi (). dpi: days postinfection.

(a)

(b)