The Disease Burden of Hereditary Angioedema: Insights from a Survey in French-Canadians from Quebec

Table 1

Demographics and clinical characteristics.

Characteristic	Full sample (n = 35), median (min, max) or n (%)
Age (years)	46 (16, 73)
Sex
Male	7 (20%)
Female	28 (80%)
Marital status
Common-law	9 (26%)
Married	16 (46%)
Single	10 (29%)
Employed	19 (54%)
HAE type
Type I	16 (46%)
Type II	1 (3%)
HAE nC1-INH	15 (43%)
Unknown	3 (9%)
Age at first HAE symptoms (years)^†	16 (1, 69)
Age at HAE diagnosis (years)	34 (2, 69)
Diagnostic delay (years)^‡	10 (0, 44)
Diagnosing doctor
Internist	6 (17%)
Immunologist/allergist	26 (74%)
Gastroenterologist	1 (3%)
Hematologist/oncologist	1 (3%)
Dermatologist	1 (3%)
Family screening
All	1 (3%)
Only some members	20 (57%)
No	13 (37%)
Do not know/NA	1 (3%)
Family deaths due to HAE	4 (11%)

HAE, hereditary angioedema; HAE nC1-INH, HAE with normal C1 inhibitor; NA, not applicable. ^†One participant did not respond to this question (n = 34). ^‡Two participants were excluded from the calculation as one respondent with HAE nC1-INH did not report their age at first symptom, and another participant with HAE type I identified as having received their diagnosis prior to experiencing their first symptom (n = 33).