An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence

Figure 4

Effect of UP360 on senescence-associated β-galactosidase cells. Mice (n = 10) were injected with D-galactose at 500 mg/kg subcutaneously daily for 9 weeks to induce accelerated aging. Mice were treated with the Aloe-based composition, UP360, starting week 5 and immunized at the end of week 7 (start of week 8). Necropsy was done at the end of week 9. Thymus tissues collected from mice treated with 200 mg/kg of UP360, normal control, and D-gal control were used for senescence-associated β-galactosidase staining. vs D-gal control; vs D-gal control.